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Project ongoing · Quantum computing

Quantum

We use quantum computing to read medical images better.

the layers of a QCNN on N qubits
log N
for each convolution gate
2 qubits
the qubits measured at each pooling step
1 out of 2
from the image to the class
4 steps

For people who come from physics, computer science, medicine

Take part in Quantum

The problem

To recognise a tumour in an MRI scan, a convolutional neural network, a CNN, learns from thousands of examples. In medicine the examples are few, and the labels are set by doctors who do not always agree with each other, or even with themselves at a later time.

With data like this, large CNNs memorise the errors too and generalise poorly. Measuring them is difficult too: in two competitions on Kaggle with fewer than 1000 test cases, the gap between the public leaderboard and the private one was bigger than the gap between the winner and the top 10%.

The qubit and the Bloch sphere

A bit is worth 0 or 1. A qubit can be in a superposition of the two: its state is a point on the surface of a sphere, the Bloch sphere. At the north pole there is |0⟩, at the south pole |1⟩, on the equator the halfway superpositions, like |+⟩ and |−⟩.

|ψ⟩ = cos(θ/2) · |0⟩ + e^(iφ) · sin(θ/2) · |1⟩

θ   from 0 to π, the latitude measured from the north pole
φ   from 0 to 2π, the longitude on the equator

point on the sphere = (sin θ · cos φ, sin θ · sin φ, cos θ)
Every pure state of a qubit, up to a global phase that does not change any measurement.

Quantum logic gates are rotations of the sphere. X, Y and Z turn the state by half a turn around their axes; the Hadamard gate turns around the axis halfway between x and z, and takes |0⟩ to |+⟩.

The states on the axes
|0⟩north pole+z axis
|1⟩south pole−z axis
|+⟩equator+x axis
|−⟩equator−x axis
|+i⟩equator+y axis
|−i⟩equator−y axis

The quantum convolutional network

A QCNN brings the idea of CNNs to qubits. The convolution is a row of two-qubit gates, the same across the whole layer, on pairs of neighbouring qubits. Pooling measures half the qubits and uses the results to rotate the ones that remain. Layer after layer the qubits halve, until a measurement gives the class.

The advantage is in the numbers: on N qubits, about log N layers are enough, and the parameters to learn grow as log N. And it has been shown that a QCNN does not fall into barren plateaus, the flat plateaus where the training of many quantum circuits stalls.

The active qubits, layer after layer. An example with 8 qubits: at each pooling step half of them are measured.
The numbers in the chart
LayerQubit
Input8 qubit
After the first pooling4 qubit
After the second2 qubit
Output1 qubit

What we know and what we do not know

Papers from 2025 and 2026 show that many QCNNs used today can be efficiently simulated even on a classical computer, because they work well mainly on data that is easy to read with local measurements.

On brain MRI scans the published numbers are still low. This is why we do not promise a quantum advantage: our work is to measure it, on equal terms, against classical methods and on the same data.

A 4-qubit QCNN on brain MRI scans. Accuracy in the preprint by Nugraha and colleagues, 2025, arXiv:2509.02582, not yet peer-reviewed.
The numbers in the chart
TaskAccuracy
Two classes (tumour or not)from 88 to 89%
Four classes (three tumours or none)from 52 to 62%

The path of the project

  1. 1A medical image, for example a brain MRI scan.
  2. 2Processing on a real quantum computer.
  3. 3Comparison with the other methods.
  4. 4Classification: which group the image belongs to.

As of April 2026 the quantum code is ready for testing.

The public data

For this problem there are public collections of brain-tumour MRI scans, already labelled. The main ones:

Collections of MRI scans
Brain Tumor MRI, Kaggle7,200 images4 classes: glioma, meningioma, pituitary, no tumour
Figshare, Cheng and colleagues3,064 imagesfrom 233 patients, 3 types of tumour
BraTS 20212,040 patients4 MRI sequences, with the tumour outlines

Where we are

  1. April 2026We presented the project at Palazzo della Borsa: the quantum code is ready for testing.
  2. Next stepRun the whole pipeline on a real quantum computer and compare it with classical methods, on the same data.

Photos

The presentation of Quantum, with the image of a brain on the screen
Palazzo della Borsa, April 2026
The presentation of Quantum on stage, with a full hall
Palazzo della Borsa, April 2026

Videos

People on the project

Who we do it with

  • Università di Genova

All the partners

Sources

  • Cong, Choi and Lukin, Quantum convolutional neural networks, Nature Physics, 2019.
  • Pesah and colleagues, Absence of Barren Plateaus in Quantum Convolutional Neural Networks, Physical Review X, 2021.
  • McClean and colleagues, Nature Communications, 2018; Bermejo and colleagues, PRX Quantum, 2026.
  • Karimi and colleagues, Medical Image Analysis, 2020; Varoquaux and Cheplygina, npj Digital Medicine, 2022.
  • Nugraha and colleagues, arXiv:2509.02582, 2025.
  • IBM Quantum Learning, Bloch sphere.
  • Presentation at the Deep-Tech Showcase, Palazzo della Borsa, 21 April 2026.

Do you want to work on it?

You do not need experience and you do not need a CV. Write to us: we invite you to the next meeting, where you meet the team.

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